Jumana Alhaj Abed

POSTDOCTORAL FELLOW

Ph.D. in Cell and Molecular Biology

Southern Methodist University

RESEARCH

I am interested in understanding the structure of homolog pairing, its functional consequences, and its relationship to epigenetic marks using super-resolution microscopy and Hi-C.

PUBLICATIONS

The genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos.

Jelena Erceg, Jumana AlHaj Abed, Anton Goloborodko, Bryan R. Lajoie, Geoffrey Fudenberg, Nezar Abdennur, Maxim Imakaev, Ruth B. McCole, Son C. Nguyen, Wren Saylor, Eric F. Joyce, T. Niroshini Senaratne, Mohammed A. Hannan, Guy Nir, Job Dekker, Leonid A. Mirny, Ting (C.-ting) Wu. Nat Commun. 2019 Oct 3;10(1):4486. DOI:10.1038/s41467-019-12211-8

Highly Structured Homolog Pairing Reflects Functional Organization of the Drosophila Genome.

Jumana AlHaj Abed, Jelena Erceg, Anton Goloborodko, Son C. Nguyen, Ruth B. McCole, Wren Saylor, Geoffrey Fudenberg, Bryan R. Lajoie, Job Dekker, Leonid A. Mirny, Ting (C.-ting) Wu. Nat Commun. 2019 Oct 3;10(1):4485. DOI:10.1038/s41467-019-12208-3

Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling.

Guy Nir, Irene Farabella, Cynthia Pérez Estrada, Carl G. Ebeling, Brian J. Beliveau, Hiroshi M. Sasaki, S. Dean Lee, Son C. Nguyen, Ruth B. McCole, Shyamtanu Chattoraj, Jelena Erceg, Jumana AlHaj Abed, Nuno M. C. Martins, Huy Q. Nguyen, Mohammed A. Hannan, Sheikh Russell, Neva C. Durand, Suhas S. P. Rao, Jocelyn Y. Kishi, Paula Soler-Vila, Michele Di Pierro, José N. Onuchic, Steven P. Callahan, John M. Schreiner, Jeff A. Stuckey, Peng Yin, Erez Lieberman Aiden, Marc A. Marti-Renom, C.-ting Wu. PLOS Genetics, December 26, 2018 https://doi.org/10.1371/journal.pgen.1007872

De novo recruitment of Polycomb-group proteins in Drosophila embryos.

Jumana AlHaj Abed, Elnaz Ghotbi, Piao Ye, Alexander Frolov, Judith Benes, Richard S. Jones. Development, November, 2018, 145: dev165027 doi: 10.1242/dev.165027

H3K36me3 key to Polycomb-mediated gene silencing in lineage specification.

AlHaj Abed, J. and R.S. Jones. Nat Struct Mol Biol. 2012. 19(12):1214-5.

Mapping Polycomb Response Elements at the Drosophila melanogaster giant locus.

AlHaj Abed, J., C. L. Cheng, C. R. Crowell, L. L. Madigan, E. Onwuegbuchu, S. Desai, J. Benes, R. S. Jones. G3 2013. 3(12):2297-2304.